People
- Department of Physiology
- About Physiology and Biophysics
-
Education
- Physiology and Biophysics Educational Programs Home
- Graduate Program
- Undergraduate Research Experience
- Seminar and Lecture Series
- Seminar Series Archives
-
Research
- Physiology and Biophysics Research Home
- Core Facilities
- Programs
- Graduate Program Research
- Publications
- Research Links
- Resources
Main Content
Research methods
Zhen Wang, PhD
 | Assistant Professor Office: G262; (601) 984-1250 Lab: G253; (601) 984-1832 |
Areas of expertise
- General: Cardiovascular and renal physiology, molecular biology
- Specific: Diabetic nephropathy, leptin signaling pathway and obesity, hypertension
Research methods
- Utilizing chronically instrumented rodents for 24 hr/day computerized-cardiovascular monitoring of BP and HR
- Comprehensive renal, cardiac and metabolic function measurements in chronically instrumented rodents
- Metabolic functions, including appetite, VO2 and energy expenditure measurement
- Chronic IV and intracerebroventricularly (ICV) infusion
- Breeding, genotyping and validation of different Cre-Lox genetically engineered mice
- Molecular, and biochemical assays (RT-PCR, Western Blot, IHC, ELISA, etc.)
Current projects
- Mechanisms of hypertensive diabetic nephropathy: role of mitochondrial dysfunction and ER stress
- Role of negative regulators of leptin signaling (SOCS3) in modulating leptin's actions